منابع مشابه
ENT manifestations of Wegeners granulomatosis.
Wegeners granulomatosis is a necrotizing granulomatous vasculitis with multisystemic involvement. We present two cases of Wegener's presenting with otological manifestations as the first symptom. These symptoms are subtle and diagnosis may be easily overlooked. Hence a high index of suspicion is required. Early diagnosis and treatment goes a long way in improving the outcomes and in preventing ...
متن کاملOtologic Wegener's granulomatosis.
Wegener’s granulomatosis (WG) is a systemic vasculitic disease characterized by necrotizing granulomas and vasculitis of small vessels.1,2 Upper airway tract involvement is frequent over the course of the disease.1,3 Cytoplasmatic pattern antineutrophil cytoplasmic antibodies (c-ANCA) are highly specific for WG in the active phase.1,3 Proteinase 3-ANCA (PR3-ANCA) positivity is usually associate...
متن کاملWegener Granulomatosis: Otologic Manifestation as First Symptom
Introduction Wegener granulomatosis is a systemic vasculitis affecting small and medium-sized vessels of the upper and lower respiratory tract and kidneys. Objective To describe a case of Wegener disease with atypical manifestation. Resumed Report We describe the case of a 50-year-old woman with chronic otitis media and sensorineural hearing loss as the primary symptoms, without other manifesta...
متن کاملWegener's granulomatosis presenting with otologic manifestations.
1. Cotch MF, Hoffman GS, Yerg DE, Kaufman GI, Targonski P, Kaslow RA. The epidemiology of Wegener's granulomatosis. Estimates of the five-year period prevalence, annual mortality, and geographic disease distribution from population-based data sources. Arthritis Rheum. 1996;39(1):87-92. 2. McDonald TJ, Deremee RA. Wegener's granulomatosis. Laryngoscope. 1983;93(2):220-31. 3. Fauci AS, Haynes BF,...
متن کاملNeutrophil chemotaxis in Wegeners granulomatosis and idiopathic pulmonary fibrosis
Background: The presence of anti-neutrophil cytoplasmic antibodies (ANCA) in Wegeners granulomatosis (WG), implicate the neutrophil as a key effector cell. Previous studies have reported elevated neutrophil counts in the lung although the determinants of neutrophil chemotaxis in the WG lung are unknown. Methods: BALF cell counts, myeloperoxidase (MPO) and chemokines were measured in 27 patient...
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ژورنال
عنوان ژورنال: Acta Otorrinolaringologica (English Edition)
سال: 2013
ISSN: 2173-5735
DOI: 10.1016/j.otoeng.2013.11.001